In addition to her role as Dana Barrett in the Ghostbusters films, Sigourney Weaver is well known for her roles as Ellen Ripley in the Alien films.
Ghostbusters: The Video Game
According to Vivendi Executive Producer John Melchior, Weaver was never contacted to reprise her role for Ghostbusters: The Video Game despite Terminal Reality's Creative Director Drew Haworth writing she turned down an offer to reprise the role. Allegedly, she tried to come aboard upon learning Bill Murray had agreed to the project, but development was too far along by that point. 
- Sigourney Weaver auditioned for the role of Dana by acting like a dog.
- On the first day of filming at the New York City Public Library, Sigourney Weaver visited the set to introduce herself to Bill Murray. He in turn picked her up and carried her down Fifth Avenue calling her by her real name, "Susan."
- During filming of the first movie, Sigourney Weaver would go to a corner to prepare herself for a scene but Bill Murray would sneak up behind her and goof around like tickle her or lift her up.
- Sigourney Weaver came up with the "game show host" line instead of the scripted "used car salesman" one.
- Sigourney Weaver was sealed inside the charred Terror Dog so there was an urgency to do the sequence quickly. Ivan Reitman made the sequence seem slower by repeating shots on angles.
- In the "Visitation" back up story from Ghostbusters Volume 2 Issue #7 and Ghostbusters Volume 2 Issue #8, the teacher is visually based on Sigourney Weaver.
- On the Regular Cover of Ghostbusters 101 #1, the map credit references Sigourney Weaver.
- On page 11 of Ghostbusters Year One Issue #2, in panel 3, on Peter's locker door is an official 8x10 photograph of Sigourney Weaver in costume as Dana from the first movie.
- On page 2 of Ghostbusters Year One Issue #3, Dana's outfit is based on an outfit worn by Sigourney Weaver's character Lauren Slaughter in the 1986 movie "Half Moon Street".
- Playboy "The Untold Story of the Ghostbusters Video Game that was Almost a Masterpiece" 7/13/16
- IGN Blogs "The Storyline and Characters" 5/12/09
- Ivan Reitman (2005). Ghostbusters- Commentary (2005) (DVD ts. 17:18-17:37). Columbia TriStar Home Video. Ivan Reitman says: "And um actually agreed to audition. She came into my office and not like I'm giving anything away saying she turned into a dog at some point in this film and uh I remember her getting up on the couch and actually auditioning like a dog and I knew at that point she had to be in the film. "
- Sigourney Weaver (2009). Ghostbusters- Slimer Mode (2009) (Blu-Ray ts. 24:10-24:34). Columbia TriStar Home Video. Sigourney Weaver says: "I was, you know, a huge fan of Bill Murray's, actually, but I met him the first day they shot at the public library, and there Bill was in a suit and stuff and I kind of went over and introduced myself. And before I knew it, he had picked me up and was carrying me down 5th Avenue calling me Susan, which is my real name."
- Joe Medjuck (1999). Ghostbusters- Commentary (1999) (DVD ts. 27:04-27:13). Columbia TriStar Home Video. Joe Medjuck says: "And she would go off into a corner to prepare herself for a scene, and Bill would sneak up behind her and tickle her or something. Bill would like to be in mid-sentence before he stepped onto the set and..."
- Ivan Reitman (1999). Ghostbusters- Commentary (1999) (DVD ts. 27:14-27:17). Columbia TriStar Home Video. Ivan Reitman says: "Or lift her up. He likes lifting women."
- Ivan Reitman (1999). Ghostbusters- Commentary (1999) (DVD ts. 28:05-28:07). Columbia TriStar Home Video. Ivan Reitman says: "Actually, that was hers. That was Sigourney's line."
- Harold Ramis (1999). Ghostbusters- Commentary (1999) (DVD ts. 28:09-28:12). Columbia TriStar Home Video. Harold Ramis says: "We had a line, "You're more like a used car salesman" in the script. She said, "You're more like a game-show host.""
- Harold Ramis (1999). Ghostbusters- Commentary (1999) (DVD ts. 01:36:21-01:36:27). Columbia TriStar Home Video. Harold Ramis says: "I remember there was a little bit of hurry up to this 'cause she was actually sealed inside that thing."
- Ivan Reitman (1999). Ghostbusters- Commentary (1999) (DVD ts. 01:36:30-01:36:39). Columbia TriStar Home Video. Ivan Reitman says: "And there's just so much that this could take. Although, in the cutting, actually, I increased how long it took to get her out by repeating shots on angles."